How do the Stem Cells and Exosomes Work for Hair Regeneration?

Stem cells and exosomes act in the body through several mechanisms. They do NOT become part of a patient’s DNA, which means they do not engraft into the person’s existing cells. The predominant method of action is thought to be through paracrine mechanisms, which means “cell to cell” interaction.

They act through:

1. Angiogenesis – provokes formation of new blood vessels.

2. Reduce inflammation– Hair loss is associated with significant inflammation, and the regenerative biologics reduce it nicely.

3. Immune system modulation – the stem cells and exosomes modulate the immune system very differently than steroids. Instead of blanketly suppressing the immune system, the regenerative biologics tamp down the harmful processes while amping up the beneficial ones. This includes ramping up production of several helpful growth factors and cytokines, while tamping down harmful ones.

4. Cellular signaling – the biologics are able to perform “cell to cell” communication. This promotes recipient cells to proliferate their growth factor production, protein production and regenerate tissues that are damaged.

5. Prevent cell death – most cells have a timed death, where they are only allowed to live a certain length of time. This is called apoptosis. The regenerative biologics allow normally functioning cells to live longer, and spare them from the pre-programmed death.

6. Preventing scar tissue – Hair loss patients may experience significant scarring throughout the scalp. Once that scar tissue forms, it becomes nonfunctional. Stem Cells and exosomes are great at preventing scar tissue (anti-fibrosis).